GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | trans | rs1056667 | 1 | rs4713006 | chr6:26519872 | ZNF322B | chr9:99957633-99961910:- | 0.54 | 10.3 | 1.35E-22 | Educational attainment |
| THCA | trans | rs1056667 | 1 | rs4713008 | chr6:26538268 | ZNF322B | chr9:99957633-99961910:- | 0.54 | 10.31 | 1.21E-22 | Educational attainment |
| THCA | trans | rs965513 | 1 | rs4743130 | chr9:100546040 | ABCC11 | chr16:48200822-48281479:- | 0.29 | 5.9 | 6.75E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs4743130 | chr9:100546040 | BMPR1A | chr10:88516396-88684944:+ | -0.24 | -6.21 | 1.13E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs4743130 | chr9:100546040 | CENPJ | chr13:25456414-25497085:- | 0.22 | 5.98 | 4.36E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs4743130 | chr9:100546040 | CLDN2 | chrX:106143394-106174091:+ | 0.27 | 6.29 | 7.37E-10 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs4743130 | chr9:100546040 | EML5 | chr14:89081205-89259157:- | 0.29 | 6.79 | 3.32E-11 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs4743130 | chr9:100546040 | EPDR1 | chr7:37960163-37991539:+ | 0.32 | 7.17 | 2.94E-12 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs4743130 | chr9:100546040 | GGT5 | chr22:24615623-24641110:- | 0.26 | 5.99 | 4.03E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs4743130 | chr9:100546040 | LRRC42 | chr1:54412037-54433839:+ | -0.24 | -6.22 | 1.08E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs4743130 | chr9:100546040 | NKX6-1 | chr4:85414436-85419387:- | 0.5 | 8.8 | 2.53E-17 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs4743130 | chr9:100546040 | PLCE1 | chr10:95753746-96088146:+ | 0.27 | 6.26 | 8.51E-10 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs4743131 | chr9:100554907 | BMPR1A | chr10:88516396-88684944:+ | -0.24 | -6.3 | 6.58E-10 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs4743131 | chr9:100554907 | CLDN2 | chrX:106143394-106174091:+ | 0.26 | 6.02 | 3.46E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs4743131 | chr9:100554907 | EML5 | chr14:89081205-89259157:- | 0.3 | 6.88 | 1.9E-11 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |